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Federated Bayesian Surveillance of Mechanical Thrombectomy Adverse Events
US & West ·
The work treats population-scale adverse-event surveillance as a distinct belief layer of a surgical digital twin, evaluated with a federated Bayesian protocol under formal privacy guarantees: sites exchange only differentially private natural-parameter updates. Benchmarking uses the full FDA MAUDE cohort for thrombus-retrieval catheters — 8,617 reports, 6,491 classified into five complication classes across eight manufacturer sites.
Why it matters
It demonstrates how to pool fragmented industry data for risk estimation without centralising sensitive information — a transferable pattern for sectoral digital twins.
The study examines how far a DT-R2S2R pipeline can substitute for real target-region data: recorded driving clips are reconstructed in a georeferenced digital twin and a diffusion model is conditioned on geometrically aligned simulator renderings, yielding a digital-twin-grounded Sim2Real model.
ONDT is a modular, virtualized, cloud-native experimentation framework for O-RAN introduced within the SUNRISE-6G project. It automates rApp/xApp onboarding, RAN scenario configuration, KPM collection and closed-loop control validation, letting AI/ML control algorithms be tested without the risks and costs of live networks.
Using Willems' fundamental lemma, a single offline input-output trajectory serves as an implicit model of a linear time-invariant system, with online operation needing only past measurements. Bounded measurement noise is handled in both stages, and recursive feasibility plus practical exponential stability are established.
